What is dornase alfa used for in cystic fibrosis treatment?

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Dornase alfa is an enzyme specifically used in the management of cystic fibrosis, and its primary function is to decrease the viscosity of mucus in the lungs. In cystic fibrosis, patients produce thick and sticky mucus that can obstruct airways and lead to respiratory complications. Dornase alfa works by breaking down the DNA in the mucus, which reduces its thickness and makes it easier to expectorate. This action helps improve lung function, decreases the frequency of respiratory infections, and enhances overall respiratory health for individuals with cystic fibrosis.

The other options do not accurately describe the role of dornase alfa. While improving arterial oxygen levels can be a result of better mucus clearance, dornase alfa’s mechanism does not directly stimulate this outcome. It also does not treat infections directly or stimulate appetite, which are not its intended uses.

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