What is a known side effect of high doses of Lasix in children with cardiovascular disorders?

High doses of Lasix (furosemide) can lead to hypokalemia, which is a known side effect, particularly relevant in pediatric patients with cardiovascular disorders. Lasix is a loop diuretic that works by inhibiting the reabsorption of sodium and chloride in the renal tubules, leading to increased urine output. This increased excretion can result in the loss of potassium, an essential electrolyte, causing hypokalemia.

In children, maintaining electrolyte balance is crucial, especially in those with preexisting cardiovascular conditions where the body may already be under stress. Hypokalemia can lead to significant complications, including arrhythmias, muscle weakness, and impaired function of the heart, all of which can exacerbate underlying cardiovascular issues.

The other options, while related to potential concerns in pediatric patients receiving treatment, do not share the same direct link with high doses of Lasix. Weight gain, insomnia, and bradycardia are not commonly associated with this medication's use, especially at high doses, and monitoring for hypokalemia remains a critical focus in the management of children on loop diuretics.