What are common symptoms of Reye syndrome?

Reye syndrome is a serious condition that primarily affects children and is characterized by specific symptoms related to liver dysfunction and neurological impairment. The correct answer highlights the presence of liver dysfunction, which is indicated by elevated liver enzymes, and cerebral edema, which involves swelling of the brain.

In Reye syndrome, the combination of these symptoms results from a harmful reaction to certain medications (most notably aspirin) during a viral infection, leading to mitochondrial dysfunction. The liver damage can cause an accumulation of fatty acids, while the cerebral edema can lead to increased intracranial pressure, potentially resulting in severe complications if not treated promptly.

While severe headache and vomiting can occur, they are not definitive indicators of Reye syndrome, as they can also relate to various other conditions. Skin rashes and allergic reactions are not associated with Reye syndrome and would suggest an entirely different issue. Seizures and fever, although potentially present in various illnesses affecting children, do not specifically define Reye syndrome, where the hallmark issues are related to liver and brain involvement.